and reset ed.] Get a printable copy (PDF file) of the complete article (267K), or click on a page image below to browse page by page. Define and give examples of senescence of cells and organisms. Senescence, or biological aging, is the breakdown of the physical body as people grow older. Replicative senescence appears to be a fundamental feature of somatic cells, with the exception of most tumour cells and possibly certain stem cells. Additional Physical Format: Online version: Comfort, Alex, 1920-2000. We haven't found any reviews in the usual places. Biology of senescence. 17: THE DISTRIBUTION OF SENESCENCE . THE NATURE AND CRITERIA OF SENESCENCE . Alex Comfort. Senescence represents age-related decline in fitness [Modified from Khan Academy] Senescence is the age-related decline in an organism’s ability to survive and reproduce. Abstract : This is an extensively revised version of The biology biology Subject Category: Disciplines, Occupations and Industries see more details of ageing published in 1954, and includes a great deal of new material that has since accumulated in the expanding field of gerontology. 0 Reviews. How do cells sense the number of divisions they have … Ageing: The Biology of Senescence Hardcover – Import, January 1, 1964 by Alex Comfort (Author) See all formats and editions Hide other formats and editions. Churchill Livingstone, 1956 - Aging - 414 pages. Price New from Used from Hardcover "Please retry" $14.48 — $14.48: Hardcover, Import, January 1, 1964: $16.27 — $5.94: Hardcover New York, Rinehart, 1956 (OCoLC)606098493: Document Type: The Biodiversity Heritage Library works collaboratively to make biodiversity literature openly available to the world as part of a global biodiversity community. This permanent state entails benefits and detriments for the organism in which the cells live. Contents. . What people are saying - Write a review. This book describes the fundamental process of senescence, and reviews a new concept developed by a number of research groups that is based on cellular senescence and its secretome. From inside the book . Full text Full text is available as a scanned copy of the original print version. Most cells cannot divide indefinitely due to a process termed cellular or replicative senescence. The Biology of Senescence A Translational Approach. Cellular senescence is a state in which cells can no longer divide. Lee and Schmitt discuss how the classical view of senescence as a static, terminally differentiated state has changed to that of a dynamic, reversible condition with diverse roles in tumour biology. Ageing: the biology of senescence by Alex Comfort, 1964, Holt, Rinehart and Winston edition, in English - [Rev. Whereas cellular senescence was first attributed to tumor suppression and aging, more recent research has found that it also promotes cancer and tissue repair. 1964 pp.xvi + 365 pp. The application of molecular biology techniques to the study of leaf senescence has, in the last few years, enabled the isolation and characterization of a large range of cDNA clones representing genes that show increased expression in senescing leaves. As soon as an organism … The biology of senescence. Authors (view affiliations) Bernard Swynghedauw; Book. 42: The Biology of Senescence. Cellular Senescence Definition. The exception of most tumour cells and organisms appears to be a fundamental feature of somatic,. Text is available as a scanned copy of the original print version collaboratively to make literature... Divisions they have … Define and give examples of senescence by Alex Comfort 1964. 414 pages the physical body as people grow older grow older senescence is a in. 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